Zev A Wainberg Selected Research

Colorectal Neoplasms (Colorectal Cancer)

1/2024	Lymph-node-targeted, mKRAS-specific amphiphile vaccine in pancreatic and colorectal cancer: the phase 1 AMPLIFY-201 trial.
12/2023	Phase Ib/II Study of the Efficacy and Safety of Binimetinib (MEK162) Plus Panitumumab for Mutant or Wild-Type RAS Metastatic Colorectal Cancer.
9/2022	Efficacy and safety of dilpacimab (ABT-165) versus bevacizumab plus FOLFIRI in metastatic colorectal cancer: a phase II study.
1/2021	Reducing Skin Toxicities from EGFR Inhibitors with Topical BRAF Inhibitor Therapy.
1/2019	Initial Report of Second-Line FOLFIRI in Combination with Ramucirumab in Advanced Gastroesophageal Adenocarcinomas: A Multi-Institutional Retrospective Analysis.
1/2019	Identification of Actionable Fusions as an Anti-EGFR Resistance Mechanism Using a Circulating Tumor DNA Assay.
1/2018	Optimising the use of cetuximab in the continuum of care for patients with metastatic colorectal cancer.
12/2017	A Multi-Arm Phase I Study of the PI3K/mTOR Inhibitors PF-04691502 and Gedatolisib (PF-05212384) plus Irinotecan or the MEK Inhibitor PD-0325901 in Advanced Cancer.
10/2017	Randomized Phase II Trial of Parsatuzumab (Anti-EGFL7) or Placebo in Combination with FOLFOX and Bevacizumab for First-Line Metastatic Colorectal Cancer.
2/2017	A phase 1 dose-escalation and expansion study of binimetinib (MEK162), a potent and selective oral MEK1/2 inhibitor.

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Zev A Wainberg Research Topics

Disease

58	Neoplasms (Cancer) 02/2024 - 02/2007
33	Adenocarcinoma 03/2024 - 01/2013
18	Colorectal Neoplasms (Colorectal Cancer) 01/2024 - 07/2007
16	Stomach Neoplasms (Stomach Cancer) 11/2023 - 03/2010
9	Pancreatic Neoplasms (Pancreatic Cancer) 03/2024 - 12/2015
9	Disease Progression 01/2023 - 12/2015
5	Neutropenia 11/2022 - 01/2019
4	Diarrhea 12/2021 - 12/2013
3	Carcinoma (Carcinomatosis) 02/2024 - 11/2020
3	Biliary Tract Neoplasms (Biliary Tract Cancer) 01/2023 - 01/2020
3	Ovarian Neoplasms (Ovarian Cancer) 01/2023 - 02/2015
3	Exanthema (Rash) 01/2021 - 02/2015
3	Neoplasm Metastasis (Metastasis) 01/2021 - 12/2010
3	Vomiting 01/2020 - 02/2017
3	Urinary Bladder Neoplasms (Bladder Cancer) 01/2020 - 03/2010
3	Colonic Neoplasms (Colon Cancer) 01/2019 - 09/2009
2	Cholangiocarcinoma 02/2024 - 01/2020
2	Triple Negative Breast Neoplasms 01/2023 - 01/2023
2	Anaplastic Thyroid Carcinoma 01/2023 - 01/2018
2	Hairy Cell Leukemia 01/2023 - 01/2023
2	Gastrointestinal Stromal Tumors (Gastrointestinal Stromal Tumor) 01/2023 - 01/2022
2	Stomatitis 11/2022 - 02/2015
2	Sepsis (Septicemia) 11/2022 - 01/2021
2	Giant Cell Tumor of Tendon Sheath 01/2021 - 07/2015
2	Septic Shock (Toxic Shock Syndrome) 01/2021 - 01/2019
2	Giant Cell Tumors (Giant Cell Tumor) 01/2021 - 07/2015
2	Nausea 01/2020 - 02/2017
2	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2020 - 01/2017
2	Anemia 01/2020 - 12/2015
2	Hypertension (High Blood Pressure) 01/2019 - 01/2013
2	Breast Neoplasms (Breast Cancer) 06/2017 - 04/2013
2	Fatigue 02/2017 - 12/2013
1	Carcinogenesis 02/2024

Drug/Important Bio-Agent (IBA)

13	Monoclonal AntibodiesIBA 02/2024 - 12/2010
10	pembrolizumabIBA 11/2023 - 10/2018
10	Oxaliplatin (Eloxatin)FDA LinkGeneric 11/2022 - 12/2013
9	Gemcitabine FDA Link 03/2024 - 12/2015
9	Bevacizumab (Avastin)FDA Link 09/2022 - 01/2012
9	Biomarkers (Surrogate Marker)IBA 02/2022 - 09/2009
7	Irinotecan (Camptosar)FDA LinkGeneric 01/2023 - 12/2013
6	ErbB Receptors (EGF Receptor)IBA 12/2023 - 07/2007
6	trametinibIBA 01/2023 - 02/2015
6	Leucovorin (Folinic Acid)FDA Link 11/2022 - 12/2013
5	dabrafenibIBA 01/2023 - 01/2018
5	Immunoglobulin G (IgG)IBA 11/2022 - 01/2017
5	Fluorouracil (Carac)FDA LinkGeneric 11/2022 - 12/2013
5	Capecitabine (Xeloda)FDA Link 06/2017 - 10/2013
4	Panitumumab (Vectibix)FDA Link 12/2023 - 07/2007
4	130-nm albumin-bound paclitaxelIBA 10/2023 - 01/2020
4	talazoparibIBA 01/2023 - 01/2017
4	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 01/2023 - 08/2014
4	Paclitaxel (Taxol)FDA LinkGeneric 01/2023 - 01/2019
4	NivolumabIBA 01/2022 - 01/2020
4	Cetuximab (Erbitux)FDA Link 01/2021 - 01/2015
4	RamucirumabIBA 01/2021 - 01/2019
3	Type 2 Fibroblast Growth Factor Receptor (Fibroblast Growth Factor Receptor 2)IBA 02/2024 - 01/2020
3	bemarituzumabIBA 02/2024 - 01/2020
3	Proteins (Proteins, Gene)FDA Link 01/2024 - 03/2010
3	gedatolisibIBA 01/2023 - 12/2017
3	Trastuzumab (Herceptin)FDA Link 01/2023 - 03/2010
3	GSK 1363089IBA 01/2022 - 01/2013
3	pexidartinibIBA 01/2022 - 07/2015
3	andecaliximabIBA 01/2021 - 01/2018
3	EnzymesIBA 01/2021 - 08/2014
3	durvalumabIBA 01/2020 - 10/2016
3	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2019 - 01/2012
3	Lapatinib (GW572016)FDA Link 06/2017 - 03/2010
3	Phosphotransferases (Kinase)IBA 01/2017 - 03/2010
2	Fibroblast Growth Factor Receptors (Fibroblast Growth Factor Receptor)IBA 02/2024 - 01/2017
2	binimetinibIBA 12/2023 - 02/2017
2	Immune Checkpoint InhibitorsIBA 11/2023 - 10/2016
2	RNA (Ribonucleic Acid)IBA 01/2023 - 02/2015
2	Cisplatin (Platino)FDA LinkGeneric 01/2023 - 01/2019
2	Tyrosine Kinase InhibitorsIBA 01/2022 - 01/2017
2	Macrophage Colony-Stimulating FactorIBA 01/2022 - 07/2015
2	sotigalimabIBA 01/2022 - 01/2021
2	PlatinumIBA 10/2021 - 01/2019
2	avelumabIBA 01/2021 - 02/2019
2	B7-H1 AntigenIBA 01/2021 - 10/2018
2	Matrix Metalloproteinase 9 (Gelatinase B)IBA 01/2021 - 11/2020
2	Circulating Tumor DNAIBA 01/2020 - 01/2019
2	Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA 01/2019 - 12/2013
2	2- amino- 8- (4- (2- hydroxyethoxy)cyclohexyl)- 6- (6- methoxypyridin- 3- yl)- 4- methylpyrido(2,3- d)pyrimidin- 7(8H)- oneIBA 12/2017 - 06/2014
2	parsatuzumabIBA 10/2017 - 01/2017
2	Epidermal Growth Factor (EGF)IBA 01/2017 - 07/2007
2	Aspartate Aminotransferases (Aspartate Transaminase)IBA 02/2015 - 01/2013
2	Adrenal Cortex Hormones (Corticosteroids)IBA 08/2014 - 02/2007
2	Cadherins (E-Cadherin)IBA 12/2010 - 03/2010
1	olaratumabIBA 03/2024
1	futibatinibIBA 02/2024
1	pemigatinibIBA 02/2024
1	erdafitinibIBA 02/2024
1	Fibroblast Growth Factors (Fibroblast Growth Factor)IBA 02/2024
1	DNA (Deoxyribonucleic Acid)IBA 01/2024
1	VaccinesIBA 01/2024

Therapy/Procedure

34	Therapeutics 01/2024 - 07/2007
23	Drug Therapy (Chemotherapy) 11/2023 - 02/2007
6	Immunotherapy 01/2024 - 01/2021
2	Neoadjuvant Therapy 01/2023 - 01/2022
2	Adjuvant Chemotherapy 02/2015 - 09/2009